Bioavailability: Forms a stable complex with copper (log stability constant = 16.4), enhancing cellular uptake and copper delivery for enzymatic processes 38.
Key Mechanisms:
Gene Regulation: Modulates >4,000 human genes, including those for collagen synthesis, DNA repair, and anti-inflammatory pathways 79.
Collagen/Elastin Stimulation: Activates fibroblasts to boost collagen I, III, elastin, and glycosaminoglycans (e.g., hyaluronic acid) 3610.
Anti-Inflammatory Action: Suppresses IL-6 and other pro-inflammatory cytokines 38.
Antioxidant Effects: Neutralizes free radicals and lipid peroxidation toxins 79.